97 Chambers Street (New York City, New York) | apartment building

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5-story Italianate residential building completed in 1858 as a store-and-loft building for the estate of Dr. David Hosack, a prominent physician (who had also been the attending surgeon at the Burr-Hamilton duel in 1804, and was one of the founders of Bellevue Hospital). The building replaced Dr. Hosack's mansion on the same site. The building became one of the most desirable in the dry goods district, and numerous tenants leased space in it throughout the years. It was converted to residential use in the late 1990s.

It is clad in sandstone above a modern (1992) metal-and-glass storefront. The upper floors have five bays of windows, with the center bays being tripartite with window openings separated by stone mullions. Triangular, segmental-arched, and flat pediments enhance the molded window openings; the openings at the top story are round-arched. The facade is capped by a metal roof cornice with brackets and modillions.

The Reade street facade, also of sandstone, is executed more simply: each story has six bays of flat-headed molded window openings; those at the fifth story are arched. The ground floor is occupied by Lot Less Closeouts store.