Chokoloskee, Florida

 island, CDP - Census Designated Place

Chokoloskee is a census-designated place (CDP) in Collier County, Florida, United States. The population was 404 at the 2000 census. Chokoloskee Island was inhabited by Indians for more than 1,500 years before European explorers reached the area. By the time Spain transferred Florida to Great Britain in 1763, the area was uninhabited. During the first three-quarters of the 19th Century, Chokoloskee Island may have been occasionally visited by Seminoles, white hunters, "Spanish Indian" fishermen from Cuba and various "refugees from justice".

Chokoloskee was briefly occupied by the United States Army during the Third Seminole War. In November of 1856 110 men of the Florida Mounted Volunteers reached Chokoloskee Island. From there, an expedition of 75 men went up the Turner River, where they burned a Seminole settlement and a couple of planted fields. After a skirmish with the Seminoles in which Captain John Parkhill was killed, the expedition returned to Chokoloskee Island to find that their base had been moved to Cape Romano, because of a lack of fresh water on the island.