I-20 West / US Highway 49 North (Jackson, Mississippi)

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Interstate 20 runs from South Carolina to west Texas. At I-95 exit 160B (I-20 exit 141) west of Florence, SC, it begins its trek westward. It travels through Columbia, SC, then Atlanta, GA. Birmingham, AL sees I-20, where it turns southwest towards Jackson, MS. I-20 continues west through Shreveport, LA and on to the Dallas-Fort Worth metroplex (where it runs on the south side of both cities). From DFW, it goes through much less populated areas. It takes traffic through Midland and Odessa, then ends at Interstate 10 near Kent, TX.

US Highway 49 goes through only two states - Mississippi and Arkansas. It begins at US 90 in Gulfport, MS. It goes through Hattiesburg and Jackson (where it is duplexed with I-220). From there, it continues through Clarksdale and then crossing into Arkansas near Helena, AR. It crosses I-40 and then goes through Jonesboro and ends at US 62 in Piggott, AR.