| About: | yes,
hi, i am vishal shah. i am bachelor of payhrmacy for north gujarat university.finishing my bachelor from himmatnagar a.p.m.c college of pharmacy . at the movement i am searching for the job. i am atteching my personal cv aswell.and cover letter as well.
COVER LETTER
HI,
ON THE BASIS OF BECHALOR OF PHARMACY DEGREE. MAIN WORK IN PHARMACEUTICAL FIELD IS REASEARCH WORK .ESPECIALLY ON MEDICINAL PLANT AND DRUGS. SELLING OF DRUGS AND PHARMACY TECHQNICIAN.
MOST IMPORTANT SUBJECTS OF PHARMACEUTICAL FIELD ARE(PHARMACOLOGY AND PHARMACOGNOSY).MY MAIN PROJECT ON MECICINAL PLANT OF ANTI CANCER DRUGS.WHICH ARE CONSIDRING CHEMICAL CONTENT ,MEDICINAL USES AND MAIN SOURCES. HAEMATOLOGICAL PERAMAETERS REQUIRE FOR DEVELOPMENT OF CHEMOTHERAPY. HAEMATOLOGICAL PERAMETERS SUCH AS (HB, RBC, WBC, SGPT, S. CREATININ AND PLETELET COUNT ). MEDICINAL PLANT CHEMTHERAPY WE DIVIDED IN FOUR GROUPS. ONE GROUP IS FOR TEST AND THE REST THREE IS FOR STANDERD DRUG. THESE HAEMATOLOGICAL PERAMATERS USED FOR THE RECOVERY OF THE CHEMOTHERAPY AFTER TWENTY DAYS. REGISTER AS A PHARMASITS IN STATE PHARMACY COUNCIL OF GUJARAT. AND ATTEND COUPLE OF INDIAN PHARMACEUTICAL CONGRESS.(IPC)
I WORKED IN IND SWIFT LIMITE AND TORRENT PHARMACEUTICAL AS MEDICAL REPRESENTATIVE. AND MEET VARIOUS SPECIALLTY OF DOCTORS SUCH AS (ORTHOPEADIC, GYNECOLOGIST, PHYSICIAN, SUERGEON,CARDIOLOGIST) ETC. AND WORKING AS A PHARMASITS IN NAND MEDICAL STORE OPP L.G. HOSPITAL . MAIN JOB IS READ THE PRECRIPTION OF DRUGS,DESPENSING OF DRUG AND REMOVAL OF EXPIRYDATE OF DRUGS. GIVE THE ORDER TO DISTRIBUTOR.
I AM LOOKING FORWARD POSITIVE REPLY.
THANKING YOU.
WITH REGARDS
VISHAL SHAH
APPLICATION
TO,
COMPANY’S NAME:
NAME OF PERSON:
ADRESS:
FROM,
VISHAL DINESHBHAI SHAH
C/1 JAYSHOMESHWARE FLAT,
NEAR JAYMALA BUS STOP,
ISHANPUR ROAD,
AHMEDABAD-380050
INDIA.
POST –GHODASAR (380050)
TELEPHONE –NO-(91-79-25322998)
SUBJECT : FOR THE POST OF
DEAR SIR/MADAM,
AS I COME TO KNOW THAT THERE IS A VACANCY IN YOR FIRM FOR THE ABOVE POST MENTION IN THE SUBJECT. I UNDERSINGED THE MOST RESPECTFULLY SUBMITT MY APPLICATION FOR SAME.
IN VIEW OF MY ACEDEMIC QUALIFICATION STATED IN THE CV IN CASE YOU ARE PLEASE TO SELECT ME FOR ABOVE POST. I ASSURE THAT I SHALL TRY MY BEST TO SATISFY THE COMPAN’S MANEGMENT WITH MY WORK IN YOUR ESTEEMEED ORGANIZATION. AND OBEY COMPANY’S TERMS AND CONDITION.
SOLICITING YOUR KIND AND FAVORABLE REPLY.
THANKING YOU.
YOURS SINCERELY,
VISHAL SHAH
CURRICULUM VITAE
NAME: VISHAL DINESH BHAI SHAH
ADRESS : C/1 ,JAYSHOMESHWARE FLAT .
NEAR JAYMALA BUS STOP
ISHANPUR ROAD
AHMEDABAD-380050
INDIA
PHONE NO- 91-79-25322998
POST GHODASAR.
DATE OF BIRTH: 03/11/1982
E-MAIL ADRESS: shahvishald@yahoo.com
1. PERSONAL STERNGTH
MAJOR STRENGTH IN PHARMACEUTICAL FIELD OF STUDY IN RESEARCH WORK .AND QIUTE A GOOD KNOWLEDGE OF PHARMACEUTICAL DRUGS AND THEIR USE.MORE INTRESRT IN ISOLATION OF MEDICINAL PLANT . BOTH THE INTREST RELATING TO PHARMACOGNOSY AND PHARMACOLOGY OF PHARMACY FIELD.
ON THE BASIS OF SELL EXPERIENCE HAVE ABILITY TO PUT THE NEW STERTEGY AND MARKETING OF THE PRODUCT SPECIALLY IN PHARMACEUTICAL FIELD.AND HAVE CAPACITY TO ACHIEVE THE TARGET ACCORDING TO THE PLAN.
ACCORDING TO THE FOOD AND MEDICAL CONTROL BOARD. QULIFIED AS A PHARMASITS WORKING AT NAND MEDICAL STORE OPP GOVERNMENT HOSPITAL(L.G.).
2. PERSONAL OBJECT
I. FINDING AND CEATING SOMTING NEW.
II. NEED FULL COMMITMENT TO ACHIEVETHE GOAL.
III. PUT YOUR 100%2525 EFFORDS
3. TECHQNICAL SKILL
I. TEAM BIULDER AND TEAM MANEGMENT
II. COMUTER SKILL(MSOFFICE)
III. DEVELOPING NEW RPODUCT IN THE MARKET
4. PRIMARY RESPONSIBILITY
• MANEGING THE TIME
• GETTING MORE INFORMATION FROM THE MARKET
• KNOWLEDGE UPDATION
• BE REPRESENTETIVE
• MAKING GOOD PLAN AND STERTEGY
5. SECONDARY RESPONSIBILITY
• IMPLEMENT TNE PLAN AND STERTERGY
• GIVING GOOD SERVICE
• MAKING A GOOD RELATIONSHIP
• TAKING ALL THE INFORMATION THE PERSON
6. EXPERRIENCE
A. PHARMASITS EXPERERIENCE
SIX MONTH EXPERIENCE AS A REGISTER PHARMASITS IN NAND MEDICAL STORE OPP. L.G. HOSPITAL.
B. SELL EXPERIENCE
SIX MONTH EXPERIENCE IN IND SWIFT (SUPER SPECIALITY DEVISION ) WORKING AS A PROFESSIONAL SERVICE REPRESENTATIVE.
ONE AND HALF YEAR EXPERIENCE IN TORRENT PHARMACEUTICAL LIMITED WORKING AS A MEDICAL REPRESENTATIVE.
C. FOOD COMPANY EXPERIENCE
• ONE YEAR EXPERIENCE IN SERVICE FOOD COMPANY AT NEWZEALAND CHRISTCHURCH. SUCH(PACKEGING, SEALLING , LEBLLING, FILLING AND QULITYOF FOOD.
7. ACHIEVEMENT:
• I GOT CERTIFICATE OF APPRICIATION IN 1994
(MATCH BOX COMPTITION FOR BLIND MENS ASSOCIATION)
• I GOT CERTIFICATE OF SPORTS EVENT IN 1994.
(IN SARDAR PATEL AND SWAMI VIVEKAND SCHOOL
CERTIFICATE IS FOR MERETONE RACE)
• I GOT CERTIFICATE OF INDIAN RED CROSS SOCIETY WITCH WAS HELD IN A.P.M...C.C. COLLEGE AT HIMMMATNAGAR IN YEAR 2002
• I GOT CERTIFICATE OF INDIAN RED CROSS SOCIETY
IN YEAR 2003 (BLOOD DONATION CAMP).
• I GOTHE CERIFICATE OF 54TH PHARMACEUTICAL CONGRESS 2002. PUNE. THEME: (BIOTHECHNOLOGY : A CHELLENG TO PHARMACY PROFESSION) PARTICIPATED IN IPC AS A DELEGATE.
• I GOT THE LETTER OF TRAINING MANEGER AGM
(MR SANJAY K. JAISWAL) SHOWS HIGH LEVEL OF COMMITMENT DURING THE TRAINING IN 2006.
• I GOT THE CERTIFICATE OF MERIT IN TRAINING IN YEAR 2006.
• I GOT THE CERTIFICATE OF EXCELLENCE IN YEAR 2006-2007 FOR ACHIEVING QATER-1.
• I GOT THE CERTIFICATE EXCELLENCE IN YEAR 2006-2007 FOR ACHIEVING QUARTER-2.
• I GOT THE CERTIFICATE OF TORRENT SUPER CUP PARTICIPATING IN CRICKET COMPITITION.
• I GOT THE CERIFICATE OF WINNING A CRICKET COMPITITION HELD IN HIMMATANAGERIN FINAL YEAR B.PHARM.
8. QUALIFICATION:
PASSING S.S.C EXAM IN MARCH 1998
PASSING H.S.C. EXAM IN MAECH 2000
PASSING BACHELOR OF PHARMACYIN MARCH-2004
GSEB : GUJARAT STAATE EDUCATION BOARD.
HNGU: HEMCHANDRACHARY NORTH GUJARAT UNIVERSITY.
9. QUALIFICATION ACHIEVEMEMT
I GOT THE CERTIFICATE OF KNOWLEDGE EXAM IN 1994.
I GOT THE MOMENTO OF FIRST BATCH OF B.PHARM PASSING IN 2004
BACHELOR OF PHARMACY DEGREE CERTIFICATE.
MIGREATION CERTIFICATE
REGISTOR AS A PHARMASITS IN GUJRAT STATE PHARMACY COUNCIL.REGISTRETION NO: G/23383.
I GOT THR CERTIFICATE OF ENGLISH LANGUAGE STUDIES IN CHRISTCHURCH COLLEGE OF ENGLISH IN 2007.
10. SUBJECT OF INTREST:
PHARMACOLOGY
PHARMACOGNOSY.
11. EXTRA ACTIVITY:
INDOOR ACTIVITY
CAROM, WACHING MOVIES, READING BOOKS(SPECIALLY MEDICAL AND PHARMAFIELD)
OUT DOOR ACTIVITY
CRICKET AND SWIMMING.
12. Reference’s:
1) SANJAY K. JAISWAL
AGM (TRAINING MANAGER)
TORRENT PHARMACEUTICAL
MOBILE NO:91-9328188890.
Bachelor of Pharmacy
________________________________________
First Year Bachelor of Pharmacy
________________________________________
101 Pharmaceutics-I (Physical Pharmaceutics)
102 Pharmaceutics - II ( Pharmaceutical Engineering And Engineering Drawing )
103 Pharmaceutical Chemistry-I
104 Human Anatomy Physiology & Health Education (APHE)
105 Advance Mathematics
106 Fundamental of Computer Applications [PC Software]
Second Year Bachelor of Pharmacy
________________________________________
201 Pharmaceutics III (Unit Operations)
202 Pharmaceutics- IV (Pharmaceutical Practice)
203 Pharmaceutical Chemistry - II (Organic Chemistry)
204 Pharmaceutical Analysis-I
205 Biochemistry & Pathophysiology
206 Pharmacognosy I
207 Pharmaceutical Jurisprudence & Ethics
Third Year Bachelor of Pharmacy
________________________________________
301 Pharmaceutical Microbiology & Biotechnology
302 Biological Pharmacy And Fermentation Technology
303 Medicinal Chemistry - I
304 Pharamceutical Analysis -II ( Instrumental Analysis And Quality Assurance)
305 Pharmacology And Chemotherapy
306 Pharmacognosy - II
307 Pharmaceutical Industrial Management
Fourth Year Bachelor of Pharmacy
________________________________________
401 Technology of Drugs & Cosmetics & GMP
402 Biopharmaceutics & Dosage Form Design
403 Medicinal Chemistry -II
404 Pharamcology & Drug Bio-Evaluation
405 Hospital And Clinical Pharmacy
406 Pharmacognosy-III ( Phytopharmaceuticals )
407 Elective
________________________________________
µ
First B. Pharm
________________________________________
101 . Pharmaceutics-I (Physical Pharmaceutics) Theory
1.States of Matter : [ 8 ]
State and selected Properties : State of matter. Change in the state of matter, latent heats and vapour pressure, sublimation-critical point, eutectic mixtures, gases, aerosols- inhalers, relative humidity, liquid complexes, Liquid crystals, glassy state, solid-crystalline and amorphous, polymorphism.
2. Micromeritics and Powder Rheology : [ 12 ]
Particle size and distribution, average particle size, number and weight distribution, particle number, methods for determining particle volume, optical microscopy, sieving, sedimentation, measurement of particle shape, specific surface, methods for determining surface area, permeability, adsorption, derived properties of powders, porosity, packing arrangement, densities, bulkiness and flow properties.
3. Surface and Interfacial phenomenon : [ 10 ]
Liquid interface, surface and interfacial tension, surface free energy, measurement of surface and interfacial tensions, free energy, spreading coefficient, adsorption at liquid interfaces, surface active agents, HLB classification, solubilization, detergency, adsorption at solid interface, solid gas and solid-liquid interface, complex films, electrical properties of interface.
4. Viscosity and Rheology : [ 9 ]
Newtonian system, Law of flow, kinematic viscosity, effect of temperature, non-Newtonian systems, pseudoplastic, dilatant, plastic, thixotropy, thixotropy in formulation, determination of viscosity: capillary, falling ball, rotational viscometers.
5. Dispersion systems : [ 15 ]
a. Colloidal dispersions : Definition, types, properties of colloids, protective colloids, applications of colloids
in pharmacy.
b. Suspensions and Emulsions : Interfacial properties of suspended particles, settling in suspensions, theory
of sedimentation, effect of Brownian movement, sedimentation of flocculated particles, sedimentation
parameters, wetting of particles, controlled flocculation, flocculation in structured vehicle, rheological
considerations, emulsions ; types, theories, physical stability.
6. Diffusion & Dissolution : [ 6 ]
Definitions, steady state diffusion, procedures and apparatus, dissolution, drug release.
7. Kinetics and drug stability: [ 8 ]
General considerations and concepts, half-life determination, influence of temperature, light, catalytic species, solvent and other factors, Accelerated stability study, expiration dating.
8. Polymer Science and Applications : [ 4 ]
Introduction and definitions, types of polymers, pharmaceutical applications, polymers as thickening agents, fabrication technology.
________________________________________
Pharmaceuticals -I (Physical Pharmaceutics) Practicals
1. Determination of latent heat, vapour pressure, critical point.
2. Studies on polymorphs their identification and properties.
3. Determination of particle size, particle size distribution and surface area using various methods of particle size analysis.
4. Determination of derived properties of powders like density, porosity, compressibility, angle of repose, etc.
5. Determination of Surface/Interfacial tension, HLB value and Critical Micelle Concentration of surfactants.
6. Study of Rheological properties of various types of systems using different viscometers.
7. Studies of different types of colloids and their properties.
8. Preparation of various types of suspensions and determination of their sedimentation parameters.
9. Preparation and stability studies of emulsions.
10. Determination of half life rate constant and order of reaction.
11. To study the influence of various factors on the rate of reaction.
12. Accelerated stability testing, shelf life determination and expiration dating of pharmaceuticals.
13. Experiment involving tonicity adjustments.
14. Experiments demonstrating the dissolution of drugs from various formulations.
Books Recommended:
1. Physical Pharmacy by Alfred Martin.
2. Remington's Pharmaceutical Sciences
3. Bentley's Pharmaceutics by E A Rawlins
4. Cooper and Gunn's Tutorial Pharmacy
________________________________________
B.P., 6 ß
First B. Pharm
________________________________________
102. Pharmaceutics - II ( Pharmaceutical Engineering And Engineering Drawing ) Theory
1. Fluid Flow: [ 8 ]
Types of flow, Reynolds number, viscosity, concept of boundary layer,
basic equations of fluid flow, valves, flow meters, manometers and measurement
of flow and pressure.
2. Material handling Systems : [ 12 ]
a. Liquid handling & storage-Different types of pumps.
b. Gas handling & storage-various types of fans, blowers and compressors.
c. Solid handling & storage- Bins, Bunkers, Conveyers, Air transport.
3. Dehumidification and humidity control : [ 5 ]
Basic concepts and definitions, wet bulb and adiabatic saturation temperatures, Psychrometric chart and measurement of humidity, applications of humidity measurement in pharmacy, eqipments for dehumidification operations.
4. Refrigeration and Air Conditioning : [ 4 ]
Principles and applications of refrigeration and air conditioning.
5. Materials of pharmaceutical plant construction : [ 6 ]
General study of composition, corrosion resistance, properties and applications
of the materials of construction with special reference to stainless steel and glass.
6. Industrial hazards and safety precautions : [ 4 ]
Mechanical, chemical, electrical, fire and dust hazards, Industrial dermatitis, Accident records etc.
7. Stoichiometry : [ 10 ]
Unit processes, material and energy balances, molecular units, mole fraction, tie substance, gas laws, mole volume, primary and secondary quantities, equilibrium state, rate process, steady and unsteady states, dimensionless equations, dimensionless formulas, dimensionless groups, different types of graphic representation, mathematical problems.
8. Heat Transfer : [ 10 ]
Source of heat, heat transfer, steam and electricity as heating media, determining of requirement of amount of steam/electrical energy, steam pressure, Boiler capacity, mathematical problems on heat transfer.
9. Corrosion and its prevention: [ 5 ]
Types, causes, theories of corrosion, methods of prevention of corrosion.
10. Packaging of materials: [ 8 ]
Function and qualities of package, hazards encountered by package, protection to be given by package, containers, closures, foils, pressure packs for pharmaceutical products.
________________________________________
Pharmaceutics II ( Pharmaceutical Engineering And Engineering Drawing ) Practicals
1. Measurement of flow of fluids and their pressure, determination of Reynolds number and calculation of frictional losses.
2. Determination of Humidity-use of Dry Bulb and Wet Bulb thermometers and psychrometric chart.
3. Experiments to demonstrate corrosion resistance of various materials.
4. Determination of Overall Heat Transfer coefficient.
5. Elementary knowledge of Engineering Drawing -Concept of plan, orthographic & isometric views, Elevation and third angle projection, notation and abbreviations used in engineering drawing.
6. Drawing of simple pharmaceutical machinery parts.
7. Introduction to Computer Aided Drawing.
Books Recommended:
1. Cooper and Gunn's Tutorial Pharmacy
2. Chemical Engineering by Badger and Banchero
3. Handbook of Chemical Engineering by Perry
4. Elementary Chemical Engineering by Max Peters
5. Unit Operations by McCabe and Smith
6. Theory & Practice of Industrial Pharmacy by Lachman & others
7. Pharmaceutics: The Science of Dosage Form Design by Aulton
8. Elementary Engineering Drawing by N. D. Bhatt
9. Machine Drawing by N. D. Bhatt
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rmulatì •
First B. Pharm
________________________________________
102. Pharmaceutics - II ( Pharmaceutical Engineering And Engineering Drawing ) Theory
1. Fluid Flow: [ 8 ]
Types of flow, Reynolds number, viscosity, concept of boundary layer,
basic equations of fluid flow, valves, flow meters, manometers and measurement
of flow and pressure.
2. Material handling Systems : [ 12 ]
a. Liquid handling & storage-Different types of pumps.
b. Gas handling & storage-various types of fans, blowers and compressors.
c. Solid handling & storage- Bins, Bunkers, Conveyers, Air transport.
3. Dehumidification and humidity control : [ 5 ]
Basic concepts and definitions, wet bulb and adiabatic saturation temperatures, Psychrometric chart and measurement of humidity, applications of humidity measurement in pharmacy, eqipments for dehumidification operations.
4. Refrigeration and Air Conditioning : [ 4 ]
Principles and applications of refrigeration and air conditioning.
5. Materials of pharmaceutical plant construction : [ 6 ]
General study of composition, corrosion resistance, properties and applications
of the materials of construction with special reference to stainless steel and glass.
6. Industrial hazards and safety precautions : [ 4 ]
Mechanical, chemical, electrical, fire and dust hazards, Industrial dermatitis, Accident records etc.
7. Stoichiometry : [ 10 ]
Unit processes, material and energy balances, molecular units, mole fraction, tie substance, gas laws, mole volume, primary and secondary quantities, equilibrium state, rate process, steady and unsteady states, dimensionless equations, dimensionless formulas, dimensionless groups, different types of graphic representation, mathematical problems.
8. Heat Transfer : [ 10 ]
Source of heat, heat transfer, steam and electricity as heating media, determining of requirement of amount of steam/electrical energy, steam pressure, Boiler capacity, mathematical problems on heat transfer.
9. Corrosion and its prevention: [ 5 ]
Types, causes, theories of corrosion, methods of prevention of corrosion.
10. Packaging of materials: [ 8 ]
Function and qualities of package, hazards encountered by package, protection to be given by package, containers, closures, foils, pressure packs for pharmaceutical products.
________________________________________
Pharmaceutics II ( Pharmaceutical Engineering And Engineering Drawing ) Practicals
1. Measurement of flow of fluids and their pressure, determination of Reynolds number and calculation of frictional losses.
2. Determination of Humidity-use of Dry Bulb and Wet Bulb thermometers and psychrometric chart.
3. Experiments to demonstrate corrosion resistance of various materials.
4. Determination of Overall Heat Transfer coefficient.
5. Elementary knowledge of Engineering Drawing -Concept of plan, orthographic & isometric views, Elevation and third angle projection, notation and abbreviations used in engineering drawing.
6. Drawing of simple pharmaceutical machinery parts.
7. Introduction to Computer Aided Drawing.
Books Recommended:
1. Cooper and Gunn's Tutorial Pharmacy
2. Chemical Engineering by Badger and Banchero
3. Handbook of Chemical Engineering by Perry
4. Elementary Chemical Engineering by Max Peters
5. Unit Operations by McCabe and Smith
6. Theory & Practice of Industrial Pharmacy by Lachman & others
7. Pharmaceutics: The Science of Dosage Form Design by Aulton
8. Elementary Engineering Drawing by N. D. Bhatt
9. Machine Drawing by N. D. Bhatt
________________________________________
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First B. Pharm
________________________________________
102. Pharmaceutics - II ( Pharmaceutical Engineering And Engineering Drawing ) Theory
1. Fluid Flow: [ 8 ]
Types of flow, Reynolds number, viscosity, concept of boundary layer,
basic equations of fluid flow, valves, flow meters, manometers and measurement
of flow and pressure.
2. Material handling Systems : [ 12 ]
a. Liquid handling & storage-Different types of pumps.
b. Gas handling & storage-various types of fans, blowers and compressors.
c. Solid handling & storage- Bins, Bunkers, Conveyers, Air transport.
3. Dehumidification and humidity control : [ 5 ]
Basic concepts and definitions, wet bulb and adiabatic saturation temperatures, Psychrometric chart and measurement of humidity, applications of humidity measurement in pharmacy, eqipments for dehumidification operations.
4. Refrigeration and Air Conditioning : [ 4 ]
Principles and applications of refrigeration and air conditioning.
5. Materials of pharmaceutical plant construction : [ 6 ]
General study of composition, corrosion resistance, properties and applications
of the materials of construction with special reference to stainless steel and glass.
6. Industrial hazards and safety precautions : [ 4 ]
Mechanical, chemical, electrical, fire and dust hazards, Industrial dermatitis, Accident records etc.
7. Stoichiometry : [ 10 ]
Unit processes, material and energy balances, molecular units, mole fraction, tie substance, gas laws, mole volume, primary and secondary quantities, equilibrium state, rate process, steady and unsteady states, dimensionless equations, dimensionless formulas, dimensionless groups, different types of graphic representation, mathematical problems.
8. Heat Transfer : [ 10 ]
Source of heat, heat transfer, steam and electricity as heating media, determining of requirement of amount of steam/electrical energy, steam pressure, Boiler capacity, mathematical problems on heat transfer.
9. Corrosion and its prevention: [ 5 ]
Types, causes, theories of corrosion, methods of prevention of corrosion.
10. Packaging of materials: [ 8 ]
Function and qualities of package, hazards encountered by package, protection to be given by package, containers, closures, foils, pressure packs for pharmaceutical products.
________________________________________
Pharmaceutics II ( Pharmaceutical Engineering And Engineering Drawing ) Practicals
1. Measurement of flow of fluids and their pressure, determination of Reynolds number and calculation of frictional losses.
2. Determination of Humidity-use of Dry Bulb and Wet Bulb thermometers and psychrometric chart.
3. Experiments to demonstrate corrosion resistance of various materials.
4. Determination of Overall Heat Transfer coefficient.
5. Elementary knowledge of Engineering Drawing -Concept of plan, orthographic & isometric views, Elevation and third angle projection, notation and abbreviations used in engineering drawing.
6. Drawing of simple pharmaceutical machinery parts.
7. Introduction to Computer Aided Drawing.
Books Recommended:
1. Cooper and Gunn's Tutorial Pharmacy
2. Chemical Engineering by Badger and Banchero
3. Handbook of Chemical Engineering by Perry
4. Elementary Chemical Engineering by Max Peters
5. Unit Operations by McCabe and Smith
6. Theory & Practice of Industrial Pharmacy by Lachman & others
7. Pharmaceutics: The Science of Dosage Form Design by Aulton
8. Elementary Engineering Drawing by N. D. Bhatt
9. Machine Drawing by N. D. Bhatt
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First B. Pharm
________________________________________
104 Human Anatomy Physiology & Health Education (APHE) (Theory)
1. Scope of anatomy and physiology and terminology used in these subjects. [ 2 ]
2. Structure of cell, its components and functions. Body fluids & its [ 2 ]
composition, transport mechanisms across the cell menbrane.
3. Elementary tissues of the human body : [ 2 ]
Epithelial, connective muscular and nervous tissues, their sub-type and characteristics.
4. Osseous system : [ 2 ]
Structure, composition and functions of skeleton, classification of joints, types of movements at joints, Disorders of joints.
5. Skeletal muscles : [ 3 ]
Their gross anatomy, physiology of muscle contraction, physiological properties of skeletal muscle and their disorders.
6. Haemopoietic system : [ 6 ]
Composition and function of blood and its elements, their disorders, blood groups and their significance, mechanism of coagulation, disorders of platelets and coagulation.
7. Lymph and Lymphatic system : [ 2 ]
Composition, formation and circulation of lymph, disorders of lymph and lymphatic system. Basic physiology and functions of spleen.
8. Cardiovascular system : [ 8 ]
Basic anatomy of the heart, physiology of heart blood vessels and circulation. Basic understanding of cardiac cycle, heart sound and electrocardiogram. Blood pressure and its regulation. Brief outline of cardiovascular disorders like hypertension, hypotension, arteriosclerosis, angina, myocardial infarction, congestive heart failure and cardiac arrhythmia.
9. Digestive System : [ 6 ]
Gross anatomy of the gastrointestinal tract functions of its different- parts including those of liver, pancreas and gall bladder. Various gastro-intestinal secretions and their role in the absorption and digestion of food, disorders of digestive system.
10. Respiratory system : [ 4 ]
Anatomy of respiratory organs, functions of respiration, mechanism and regulation of respiration, respiratory volumes and capacity.
11. Central Nervous System : [ 6 ]
Functions of different parts of brain and spinalcord. Neurohumoral transmission in the central nervous system, reflex action, electroencephalogram, cranial nerves and their functions.
12. Autonomic Nervous System : [ 2 ]
Physiology and functions of the autonomic nervous system. Mechanism of neurohumoral transmission in the A.N.S.
13. Urinary System : [ 4 ]
Various parts, structures and functions of the kidney and urinary tract. Physiology of urine formation and acid base balance. Diseases of the urinary system.
14. Reproductive system :- [ 4 ]
Male and Female reproductive system and their hormones. Physiology of menstruation, coitus and fertilization. Sex differentiation, spermatogenesis, pregnancy its maintenance and parturition.
15. Endocrine System : [ 6 ]
Basic anatomy and physiology of pituitary, thyroid, Parathyroid, Adrenals, Pancreas, Testes and ovary, their hormones and functions.
16. Sense Organs : [ 4 ]
Basic anatomy and physiology of the eye (vision), ear (hearing), taste buds, nose (smell) and skin (superficial receptors).
17. Health Education : [ 9 ]
a. Concepts of health & disease, disease causing agents and prevention of 1
disease.
b. Classification of food requirements, balanced diet, nutritional deficiency 2
disorders, their treatment and prevention, specifications for drinking water.
c. Demography and family planning : Demography cycle, family planning, 2
various contraceptive methods. Medical termination of pregnancy.
d. Brief outline of communicable diseases, their causative agents, modes of 3
transmissions and prevention (Chicken pox, measles, influenza, diphtheria, whooping cough tuberculosis, poliomyelitis, hepatitis, cholera, typhoid, food poisoning, helmenthiasis, malaria, filariasis, rabies, trachoma , tetanus, leprosy, syphilis, gonorrhea and AIDS ).
e. First Aid : Emergency treatment of shock, snake bites, burns, poisoning, 1
fractures and resuscitation methods.
________________________________________
Human Anatomy Physiology & Health Education (Practicals)
1. Study of human skeleton.
2. Study of different systems with the help of charts and models.
3. Microscopic study of different tissues.
4. Estimation of hemoglobin in blood, determination of bleeding time, clotting time R.B.C. count, TLC , D.L.C. and E.S.R.
5. Recording of body temperature, pulse rate and blood pressure, basic understanding of Electrocardiogram PQRST waves and their significance.
6. Physiological experiments on nerve-muscle preparations and heart of frog or using computer softwares or tracings.
7. Determination of vital capacity, experiments on spirometry.
Books Recommended
1. Human Physiology by C. C. Chatterjee
2. Principles of human anatomy by Tortora
3. Textbook of Medical Physiology by Guyton and Hall
4. Basic Human Physiology by Guyton
5. The Living Body by Best and Taylor
6. Elements of Human Anatomy Physiology & Health Education by Dr. Derasari
7. Practical Anatomy and Physiology by Dr. Goyal, Patel and Shah.
8. Price's Textbook of The Practice of Medicine by Ronald Scott.
________________________________________
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First B. Pharm
105 : Advance Mathematics (Theory)
________________________________________
Unit – 1 (A) Determinants and matrices: [8]
Concept of determinants, properties of determinants (with out proof) Cramers rule, matrices of order m x n. Algebra of matrices, row and column, transformation computation of inverse, simultaneous equations of inverse, simultaneous equations in two and three unknown variables solve by matrices methods.
(B) Bio statistics: [8]
Measures of central tendence (Averages) Mean, Median and Mode (Practical Problems) measures of dispersion : Range, Quartice Deviation, Mean Deviation, Standard Deviation (Practical Problems)
Unit – 2 Limit, continuity and differentiation: [16]
Limit of a function, rules of a limit (with out proof) some standard limits of all
Functions (with our proof).
Continuity and discontinuity for a polynomial functions at a point.
Defination of derivative. Rules of derivative (with out proof) Derivative of some Standard functions polynomials, implicit, exponential logaritumic and trigonometric functions higher order of derivative, maxima and minima, tangent and normal.
Unit – 3 Rolles theorem, langromge’s and cauchu’s mean value theorems [16]
L’ Hospital rule along with suitable illustration.
Unit – 4 Integral calculus: [16]
Defination of integration basic rules of integration (with out proof) integration of some standard functions integration by parts. Definite integral
application of definite integral to surface and volume revolution.
Unit – 5 Differential equation: [16]
Definition and formation of differential equation of first order and first degree. Solution of differential equations of the first order and first degree
by variable separable, homogeneous equation linear equation, bernoylli’s equation, exact equation.
Differential equations of first order and higher degree, equations solvable for p, x and y. (Lagrange’s equation, cluiraut’s form)
Book Recommended
1. Higher engineering mathematics by B. S. Grerawal
2. Mathematical statistics by J. N. Kapur & H. C. Saxena
3. A Text book of Matrices: Shairti Narayan S. Chand & Co.
4. Integral and Differential calculus: Shairti Narayan Shyamlal Charitable Trust.
5. Differential equations with application by herman betz paul B. Burcham.
6. Differential equation by varishtua & Sharma Krishna Prakashan Mandir Meerut.
________________________________________
ractiÙ o
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First B. Pharm
106 : Fundamental of Computer Applications (PC Software)
________________________________________
Theory: [80]
FUNDAMENTAL:- [15]
Introduction to Computer, Input/Output Devices, Storage Devices, Binary Conversion, Computer Classification, Applications of Computers in Pharmacy.
Introduction to Dos Commands: File Name and Different Extensions, Introduction to Windows, Use of Menu Bar, ICON, Taskbar, Desktop, My Computer, Control Panel, Window Explorer, Network Neighborhood, Recycle Bin, MS-Paint, Creating Folder, Copying & Moving Files, Deleting Files, Creating Shortcuts, Adding & Deleting From Start Menu, Adding & Removing Hardware, Scanning Disk, De-fragmentation, Security Features, Installing other Software etc.
WORD PROCESSING PACKAGE [MS WORD] [20]
Word Essentials, Typing and Editing, Copy, Cut, Paste Finding and Replacing, Auto-correct and Auto text – Reusing Text and Graphics, Alignment, Formatting Text, Formatting Paragraphs, Formatting and Sorting Lists, Page Design and Layout, Page Setup : Margins, Page Numbers, Header, Footer and Other Items, Spell Check and Grammar Use of Thesaurus, Newspaper – style Columns, Working with Tables, Mail Merge, Word Art.
SPREADSHEET PACKAGE [MS EXCEL] [20]
Concept of worksheet, Navigating Worksheet, Entering & Editing data into cells, formulas & operators. Range of cells, Moving-Copying-Transposing data, absolute and relative cell references, spell checking, insert/delete/hide/show rows/ columns, change column, width/row height, formatting data, protecting & hiding data, sorting data, searching & replacing data, built-in functions, Statistical functions, Mathematics Function, look up tables, data organization-analysis-manipulation, queries, what-if analysis, import-export of data, multiple worksheets & operations on them, Editing chart features such as formatting charts, adding legends and changing data. Pictures, file operations, printing worksheets, macros, templates, interface with other software packages, filtering data etc.
PRESENTATION PACKAGE [POWER POINT] [15]
Creating/editing slides, using text, drawings, tables, pictures, charts and other objects in slide, animation & slide transition effects, creating and running automatic slide show, macros, templates, interface with other packages. Automatic slide show.
INTERNET [10]
To Create New Internet Connection, Internet Addressing, Physical Connection, Telephone Lines, Introduction to E-mail, Creating Mail, Reading Mail, Reading Maid, Sending Mail, To create new Email Account, Web Browsers, Search Engines, Important Web sites. Browsing up the Web sites (e.g. Railway reservation, Sites of Pharmaceutical etc.)
Books Recommended:-
1. Working in Microsoft Office by Ron Mansfield
2. MS-Office by R. K. Taxali
3. PC-Software for Windows made Simple by R. K. Taxali
4. MS-Office – APTECH, TMH Publications
5. Online Help
6. Ms-Office 2000 – No Experience required – Gini Courter (BPB)
7. Mastering Ms-Office 2000 (Prof. Edition) – Courter
8. Using Microsoft Office 2000 – Helly
9. World Wide Web, Design with HTML C Xavier
10. Woody Leonhard Teaches Microsoft Office 2000 (PHP)
11. CCC – BAOU, Books of Dr. Babasaheb Ambedkar Open University
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heig) ¬
Fourth B. Pharmacy
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401. Technology of Drugs & Cosmetics & GMP [Theory]
1. Liquid dosage forms: [ 4 ]
Introduction, types of additives used, vehicles, stabilizers, preservatives, emulsifying agents, solubilizers, colors, flavours , manufacturing, packaging and evaluation of ideal suspensions and emulsions official in pharmacopoeia.
2. Semisolid dosage forms: [ 4 ]
Definitions, types, mechanisms of drug penetration through skin, factors influencing penetration, semisolid bases and their selection, general formulation of semisolids, clear gels, manufacturing procedure, evaluation and packaging.
3. Tablets: [ 12 ]
a. Introduction to types of tablets , formulation of different types of tablets, excipients, granulation techniques, machinery for large scale granulation, physics of tablet making, compression machinery , In process controls, processing problems , Evaluation parameters and equipments.
b. Coating of tablets: objectives, types of coating, film forming materials, formulation of coating solution, equipment for coating, coating process, evaluation of coated tablets , coating defects, specialized coating process.
4. Capsules: [ 8 ]
Advantages and disadvantages of capsule dosage form, size of capsules, material for production of hard gelatin capsules, formulation of hard gelatin capsules, method of capsule filling, soft gelatin capsule, shell and capsule content, importance of base absorption and minimum/gm factors in soft capsule quality control, stability testing & storage of capsule dosage forms.
5. Microencapsulation. [ 3 ]
Introduction, techniques of microencapsulation, characterisation and applications.
6. Parenteral products: [ 16 ]
a. Preformulation factors, routes of administration, vehicles- aqueous, nonaqueous; pyrogenicity, Pyrogen testing, isotonicity and methods of its adjustment, modern methods for preparing WFI
b. Formulation details, containers and closures -types, characteristics, selection.
c. Prefilling treatment- washing of containers and closures, an introduction to glass, plastic and rubber as materials of containers and closures of parentral products. preparation of solution and suspensions, filling and closing of ampoules , vials, infusion fluids, opthalmic preparations, lyophillization & preparation of sterile powders, equipment for large scale manufacturing and evaluation of parenetral products.
d. Aseptic techniques, sources of contamination and method of prevention, design of aseptic area, Laminar flow benches, services and maintenance.
7. Pharmaceutical aerosols: [ 3 ]
Definition, propellants, general formulation, containers, selection of components, manufacturing and packaging methods, pharmaceuticals applications, evaluation of aerosols.
8. Cosmetic technology: [ 6 ]
Fundamentals of cosmetic science, structure and functions of skin, hair, formulation, preparation and packaging of cosmetics for skin - Sunscreen, moisturizers, cold cream, and vanishing cream, hair - Shampoo and conditioners, dentifrice- powders, gels, paste and manicure preparations like nail polish, lipsticks, eye lashes, brief introduction on baby care products, shaving cream.
9. Packaging of pharmaceutical products: [ 4 ]
Packaging components, types, specifications, stability aspects of packaging, packaging equipments, factors influencing choice of containers, legal and other official requirements for containers, package testing.
10. Labeling of pharmaceuticals: FDA requirements. [ 2 ]
11. Good Manufacturing Practice For Pharmaceuticals: [ 10 ]
Introduction, WHO guidelines, practice of GMP- Procedure (SOP’S), Building, Equipment, Personnel, Components, Documentation, Containers, Labeling, Laboratory Control, Distribution Records, Recovery & Reprocessing .
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Technology of Drugs & Cosmetics And GMP: [Practical]
1. Preparation, evaluation and packing of liquid orals like solutions, suspensions and emulsions, ointments, suppositories, aerosols, eye drops, eye ointments, etc.
2. Preparation of pharmacopoeial extracts and galenical products utilizing various methods of extraction.
3. Formulation of various types of cosmetics for skin, hair, dentifrice and manicure preparation.
4. Experiments to illustrate preparation, stabilization, physical and biological evaluation of pharmaceutical products like powders, capsules, tablets, parenterals, microcapsules
5. Evaluation of materials used in pharmaceutical packaging.
Books Recommended:
1. Theory and Practice of Industrial Pharmacy by Lachman.
2. Remington’s Pharmaceutical Sciences.
3. Textbook of Pharmaceutical Formulation by Mithal.
4. Pharmaceutical Dosage Forms: Tablets by Lachman and others.
5. Pharmaceutical Dosage Forms: Disperse Systems by Lieberman and others.
6. Pharmaceutical Dosage Forms: Parenteral Medication by Lieberman and others.
7. Microencapsulation by Benita.
8. Pharmaceutical Dosage Forms and Drug Delivery Systems by Ansel & others.
9. GMP for Pharmaceuticals by Willig and Storker.
10. Cosmetics and Toiletries Industry by Williams and Schmitt.
11. Cosmetics: Formulation Manufacture and Quality Control by P.P. Sharma.
12. Cosmetics by Poucher.
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Second B. Pharm
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203 Pharmaceutical Chemistry - II (Organic Chemistry) (Theory)
The subject of organic Chemistry will be treated in its modern perspective keeping for the sake of convenience, the usual Classification of organic compounds.
1. Structure and Properties: [ 8 ]
Atomic structure, Atomic orbitals, Molecular orbital theory, wave equation, Molecular orbitals, Bonding and Antibonding orbitals, Co-valent bond, Hybrid orbitals, Intramolecular forces, Bond dissociation energy Polarity of bonds, Polarity of molecules, structure and physical properties, Intermolecular forces, Acids and bases.
2. Stereochemistry : [ 8 ]
Isomerism and nomenclature and associated physicochemical properties, optical activity. Stereoisomerism, specification of configuration, chirality, chiral reagents, Reaction involving stereoisomers, conformations.
3. Structure, Nomenclature, preparation and reactions of : [ 35 ]
Alkanes, Alkenes, Alkynes, Cycloalkanes, Dienes, Benzene, Polynuclear aromatic compounds, Areues, Alkyl halides, Alcoholes, Ethers, Epoxides, Amines, phenols, Aldehydes and ketones, carboxylic acids, functional derivatives of carboxylic acid, Reactive intermediates-carbocations, carbanions, carbenes, nitrene and nitrenium ions.
4. Nucleophilic aromatic substitutions; alpha-beta Unsaturated carbonyl [ 15 ]
compounds, Conservation of orbital symmetry and rules, Electrocyclic cyclo addition reactions, Sigmatrophic reactions, Neighbouring group effects, Catalysis by transition metal complexes, Stereoselective and sterospecific reactions, organic reagents used in drug synthesis like E.C.A., malonitrile, N-bromo succinamide ethylaceto acetate.
5. Heterocyclic Compounds : [ 9 ]
Chemistry of some important heterocylics contains 3,4,5,6 & 7 atoms with one or two hetero atoms like O,N,S. Preparation and properties of furan, thiophene, pyrrole, pyrimidine, imidazole
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Pharmaceutical Chemistry-II [Practical]
1. The student should be introduced to the various laboratory techniques through demonstrations involving synthesis of selected organic compounds,[e.g. aspirin, p-bromoacetanilide, anthraquinone from anthracine, reduction of nitrobenzene etc.]
2. Identification of organic compounds and their derivatives.
3. Introduction to the use of stereomodels.
4. At least five exercises in synthesis involving various heterocyclic ring systems.
5. An exercise involving stereoselective synthesis of a compound resolution of racemic DL-alanine or any other example.
6. Workshop on molecular modeling of primary, secondary and tertiary structures of proteins, molecular modeling on double helical structure of nucleic acid showing hydrogen bonding.
Books Recommended:
1.Organic Chemistry by Morrison & Boyd.
2.Organic Chemistry by Brewester & McEwan
3.Organic Chemistry Vol I & II by Finar
4.Organic Chemistry by Wingrove & S. Caret
5.Organic Chemistry by Pine & Handrickson
6.Organic Chemistry by Jerry March
7.Practical Organic Chemistry by F.G. Mann & B.C. Saunders
8.Vogel's Textbook of Practical Organic Chemistry by B.T. Furnis
9.Stereochemistry of carbon compounds by L. Eliel
10. An Introduction to the chemistry of heterocyclic compounds by R.M. Acheson .
11.Basic and Pharmaceutical Practical Chemistry by Singh and Kapoor
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Second B. Pharm
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205 Biochemistry & Pathophysiology [Theory]
Part-I Biochemistry
1. Biochemical organization of the cell and transport processes across cell [ 2 ]
membrane.
2. The concept of free energy, determination of change in free energy from [ 2 ]
equilibrium constant and reduction potential bioenergetics, production of ATP and its biological significance.
3. Enzymes : Nomenclatures, enzyme Kinetics and its mechanism of action, [ 4 ]
mechanism of inhibition, isozymes and isoenzymes in clinical diagnosis.
4. Co-enzymes : Vitamins as co-enzymes and their significance, Metals as co- [ 4 ]
enzymes and their significance.
5. Carbohydrates metabolism ; Conversion of polysaccharide to glucose- - [ 9 ]
phosphate, glycolysis and fermentation and their regulation, Gluconeogenisis and glycogenolysis, metabolism of galactose and galactosemia. Role of sugar nucleosides in biosynthesis, and pentosephosphate pathway.
6. The citric acid cycle ; Significance, reactions and energetic of the cycle, [ 3 ]
Amphibolic role of the cycle and Glyoxalic acid cycle.
7. Lipids metabolism ; Oxidation of fatty acids, beta-oxidation & energestics [ 5 ]
alpha oxidation. r-oxidation, Biosynthesis of ketones bodies and their utilisation, biosynthesis of saturated and unsaturated fatty acids, control of lipids metabolism, Essential fatty acids & eicosanoids [prostaglandens, thromboxens] phospholipids, and sphingolipids.
8. Biological oxidation - Redox-potential, enzymes and co-enzymes [ 5 ]
involved in oxidation reduction its control, The respiratory chain, its role in energy capture and its control, Energestics of oxidative phosphorylation, Inhibitors of respiratory chain and oxidative phosphorylation and, mechanism of oxidative phosphorylation.
9. Nitrogen & sulphur cycle ; Nitrogen fixation, ammonia assimilation, [ 3 ]
nitrification and nitrate assimilation, sulphate activation, sulphate reduction. Incorporation of sulphur in organic compounds, Release of sulphur from organic compounds.
10. Metabolism of Ammonia and Nitrogen containing Monomers ; Nitrogen [ 8 ]
balance, Biosynthesis of amino acids, catabolism of amino acids, conversion of amino acids to specialized products, Assimilation of ammonia, Urea cycle, metabolic disorders of urea cycle, metabolism of sulphur containing amino acids, porphyrin biosynthesis, formation of bile pigments, hyperbilirubinemia, purine nucleotide interconversion, pyrimidine biosynthesis, and formation of deoxyribonucleotides.
11. Biosynthesis of nucleic acids : Brief introduction of genetic organisation of [ 7 ]
the mammalian, genome, alteration and rearrangements of genetic material, Biosynthesis of DNA and its replication, Mutation, physical & chemical mutagenesis/carcinogenesis, DNA repair mechanism, Biosynthesis of RNA.
12. Genetic code and protein synthesis ; Genetic code, components of [ 3 ]
protein synthesis, and Inhibition of protein synthesis.
13. Regulation of gene expression. [ 2 ]
Part.II Pathophysiology
1. Basic Principles of cell injury and adaptation ; Causes of cellular [ 5 ]
injury, pathogenesis, morphology of cell injury, Intracellular alterations in lipids, proteins and carbohydrates, cellular adaptation, atrophy, hypertrophy.
2. Basic Mechanism involved in the process of inflammation and repair ; [ 5 ]
Alterations in vascular permeability and blood flow, migration of WBCs, acute and chronic inflammation, mediators of inflammation , brief outline of the process of repair.
3. Pathophysiology of common diseases ; Like Rheumatoid arthritis, gout, [ 8 ]
epilepsy, psychosis, depression, mania hypertension, Angina, congestive heart failure, [CCF], artherosclerosis, myocardial infraction, diabetes, pepticulcer, asthma, ulcerative colitis, hepatic disorders, acute and chronic renal failure, tuberculosis, urinary tract infections, Sexually Transmitted Diseases[STD], animas and common types of neoplasms.
wherever applicable the molecular basic should be discussed.
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Biochemistry & Pathophysiology [Practical]
1. To prepare standard buffers [citrate, phosphate, and carbonate] and measure pH
2. Titration curve for amino acids.
3. Separation of amino acids by two dimensional paper chromatography and gel electrophoresis
4. The separation of lipids by TLC.
5. Separation of serum proteins by electrophoresis on cellulose acetate.
6. Quantitative estimation of amino acids.
7. Quantitative estimation of proteins.
8. The identification of c-terminal amino acids of a protein.
9. The determination of glucose by means of the enzyme glucose oxides.
10. The isolation and assay of glycogen from the liner and skeletal muscle of rats.
11. Enzymatic hydrolysis of glycogen by alpha & beta amylase.
12. The isolation and determination of RNA and DNA.
13. Effect of temperature on the activity of alpha- amylase.
14. Estimation of SGOT, SGPT, ALP, and BRN in the serum.
15. Simple experiments involved in the analysis of normal and abnormal urine: collection of specimen, appearance, determination of pH, sugars, proteins, urea and creatinine.
Books Recommended :
1. Harper’s Review of Biochemistry by Martin
2. Outlines of Biochemistry by Conn and Stump
3. Biochemistry by Lehninger
4. Textbook of Biochemistry by Harron and Mazur
5. Textbook of Biochemistry by Rama Rao
6. Textbook of Biochemistry by Varunkumar Malhotra
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Second B. Pharm
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204 Pharmaceutical Analysis-I [Theory]
1. Introduction : [ 3 ]
Significance of quantitative analysis in quality control. Different techniques of analysis, preliminaries and definitions, selection of sample, precision and accuracy. Fundamental of volumetric analysis, methods of expressing concentration, primary and secondary standards.
2. Acid Base Titration: [ 5 ]
Acid base concepts, Role of the solvent, relative strengths of acids and bases. Ionization, low of mass action, common ion effect. Ionic product of water, pH, Hydrolysis of salts Henderson-Hesselbach equation, Buffer solutions, Neutralization curves, Acid-base indicators, Theory of indicators. Choice of indicators, Mixed indicators, polyprotic system, polyamine and aminoacid systems, Amino acid titration, applications in assay of H3PO4, NaOH, CaCO3 etc.
3. Oxidation Reduction Titrations: [ 5 ]
Concepts of oxidation and reduction, Redox reactions, strengths and equivalent weights of oxidizing and reducing agents, Theory of redox, redox indicator, titrations, cell representations, Measurement of electrode potential, Oxidation-reduction curves, Iodimetry and Iodometry, ceric sulphate titrations, Potassium iodate titrations, potassium bromate titrations, Titanous chloride titrations, sodium 2, 6-dichlorophenol, Iodophenol titration, potassium permanganate pharmaceutical applications.
4. Precipitation titration : [ 2 ]
Precipitation reactions, solubility products, effect of acids, temperature and solvent upon the solubility of a precipitate. Argentometric titrations, ammonium or potassium thiocyanate titrations, mercuric nitrate titrations, Mohr’s method, Volhard’s method, Fajan’s method, Gay-lussac method, pharmaceutical applications.
5. Gravimetric Analysis : [ 2 ]
Precipitation techniques, solubility products, the colloidal state, supersaturational co-precipitation. Post precipitation, digestional washing of the precipitate filtration, filter papers and crucibles, Ignition, Thermogravemetric curves, specific examples like barium sulphate, aluminium as aluminium oxide, calcium as calcium oxalate and magnesium as magnesium pyrophoshate,, organic precipitants.
6. Theoretical considerations, and application in drug analysis and quality control of the following analytical techniques will be discussed. :
1. Non-aqueous titrations. [ 3 ]
2. Complexometry. [ 3 ]
3. Potentiometry [ 3 ]
4. Conductometry. [ 3 ]
5. Calorimety. [ 3 ]
6. Polarography. [ 2 ]
7. Amperometry. [ 2 ]
8. Extraction procedure including separation of drug from excipients. [ 3 ]
9. Chromatography:- Theory , mechanism of separation, types and [ 9 ]
practical aspects and application of different chromatographic techniques. The following techniques will be discussed with relevant examples of pharmacopeial products. TLC, HPLC, GLC, HPTLC, paper chromatography and column chromatography.
10. Miscellaneous methods of analysis such as ; Diazotisation titration, [ 2 ]
Kjeldahl method of nitrogen estimation, Karlfischer titration, oxygen flask combustion, gasometry.
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Pharmaceutical Analysis -I [Practical]
The student should be introduced to the main analytical tools through demonstrations. They should have a clear understanding of a typical analytical balance, the requirements of a good balance, weights, care and use of balance, methods of weighing and errors in weighing. The students should also be acquainted with the general apparatus required in various analytical procedure.
1. Standardization of analytical weights and calibration of volumetric apparatus.
2. Acid Base Titrations: Preparation and standardization of acids and bases, some exercise related with determination of acids and bases separately of in mixture form, some official assay procedure e.g. boric acid should also be covered.
3. Oxidation reduction titrations : Preparation and standardization of some redox titrants e.g. potassium permanganate, potassium dichromate, iodine, sodium thiosulphate, etc., some exercises related to determination of oxidizing and reducing agents in the sample shall be covered. Exercises involving potassium iodate, potassium bromate, iodine solution, titanous chloride, sodium 2,6,-di chlorophenol idophenol, ceric ammonium sulphate be designed.
4. Precipitation Titrations : Preparation and standardization of titrants like silver nitrate and ammonium thiocyanate, titrations according to Mohrs Volhards and Fajans methods.
5. Gravimetric Analysis : Preparation of Gooch crucible for filtration and use of sintered glass crucible, determination of water of hydration, some exercises related to gravimetric analysis should be covered.
6. Non-aqueous Titrations : Preparation and standardization of perchloric acid and sodium/ potassium/lithium methoxides solutions, Estimations of some pharmacopoeial products.
7. Complexometric titrations : Preparations and standardization of EDTA solution, some exercises related to pharmacopoeial assays by complexometric titrations.
8. Miscellaneous determinations. Exercises, involving diazotisation, Kjeldahl, Karl-Fischer, oxygen flask combustion and gasometry methods. Determination of alcohol content in liquid galenicals, procedure [BPC] shall be covered.
9. Experiments involving separation of drug from excipients.
10. Chromatographic analysis of some pharmaceutical products.
11. Exercises based on acid base titration in aqueous and non aqueous media, oxidation-reduction titration, precipitation titrations and complex formation titrations using potentiometric technique, determination of acid base dissociation constant and plotting of titration curves using pH meter.
12. Exercises involving polarimetry.
13. Exercises involving conductometric and polarographic techniques.
Books Recommended :
1. Quantitative Chemical Analysis by Aryes
2. A Text book of Quantitative Inorganic Analysis by Vogel
3. A Text book of Pharma Analysis by Connors
4. Practical Pharma. Chemistry Part I & II by Backett and Stenlake
5. Instrumental Methods of Analysis by Willard
6. Instrumental Methods of Chemical Analysis by Ewing
7. Instrumental Methods of Analysis by Chatwal and Anand
8. The Quantitative Analysis of Drug by D.C.Garatt
9. Pharma. Analysis, Modern Methods Part I & II by James W. Munson
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206 Pharmacognosy I :(Theory)
1. Definition, history, scope and development of Pharmacognosy. [ 2 ]
2. Sources of drugs : Biological, marine, geographical and plant tissue [ 3 ]
cultures as sources of drugs.
3. Classification of drugs : Alphabetical, morphological, taxonomical, [ 3 ] pharmacological and chemical.
4. Cultivation, collection, processing and storage of crude drugs. [ 8 ]
Factors influencing cultivation of medicinal plants, types of soil and fertilizers of common use. Pest management and natural pest control agents. Plant hormones and their applications. Polyploidy, mutation and hybridization with reference to medicinal plants.
5. Quality control of crude drugs : Adulteration of crude drugs and [ 5 ]
their detection by organoleptic, microscopic, physical, chemical and biological methods of evaluation.
6. An Introduction to chemical constituents of drugs : their isolation, classification and properties & systematic pharmacognostic study of following :
1. Carbohydrates and derived products :Agar, Guar gum, Gum acacia, [ 10 ]
Honey, Isabgol, Pectin, Starch, Sterculia and Tragacanth.
2. Lipids : Bees wax, Castor oil, Coca butter, Cod-liver oil, Hydnocarpus oil, [ 8 ]
Kokum butter, Lard, Linseed oil, Rice bran oil, shark liver oil and wool fat.
3. Resins and resin combinations :Colophony, Podophyllum, Jalap, Cannabis, [ 9 ] Capsicum, Myrrh, Asafoetida, Balsam of peru, Balsam of tolu, Benzoin, Turmeric.
4. Tannins and tannin containing drugs : Gambir, black catechu, gall and [ 5 ] myrobalan.
5. Volatile oils : General methods of obtaining volatile oils from plants. [ 15 ]
Study of volatile oils of Mentha, Coriander, Cinnamon, Cassia, Lemon peel, Orange peel, Lemon grass, Citronella, Caraway, Cumin, Dill, Spearmint, Clove, Fennel, Nutmeg, Eucalyptus, Chenopodium, Cardamom, Valerian, Musk, Palmrosa, Gaultheria, Sandal wood.
7. study of fibres used in pharmacy : cotton, silk, wool, nylon, glass- wool, [ 3 ]
polyester and asbestos.
8. Study of pharmaceutical aids : talc, diatomite, kaolin, bentonite and [ 2 ]
gelatin.
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Pharmacognosy-I (Practical)
1. Morphological characteristics of plant families mentioned in theory.
2. Microscopic measurements of cells and cell contents: starch, grains, calcium, oxalate, crystals and phloem fibers.
3. Determination of leaf constants such as stomatal index, stomatal number, vein islet number, vein termination number and palisade ratio.
4. Identification of crude drugs belonging to carbohydrates and lipids
5. Preparation of herbarium sheets.
6. Identification of crude drugs mentioned in theory.
7. Study of fibers and pharmaceutical aids.
8. Microscopic studies of crude drugs and their powders underlined in the category of volatile oils.
Books Recommended :
1. Pharmacognosy by G.E.Trease and W.C.Evans
2. Text book of Pharmacognosy by T.E.Wallis
3. Pharmacognosy by V.E.Tylor,L.R.Brady and J.E.Robbers
4. Text book of Pharmacognosy by Dr.C.S.Shah and Prof. J.S.Qadry
5. Pharmacognosy by S.S.Handa and V.K.Kapoor
6. Pharmacognosy by Prof.C.K.Kokate,Prof.A.P.Purohit & S.B.Gokhale
7. Text book of Pharmacognosy by Dr. Mohammed Ali
8. The Wealth of India (Raw Material & Industrial Product)
9. Compendium of Indian Medicinal Plants Vol. I,II,III & IV
10. Cultivation and Utilization of Aromatic Plants by Atal & Kapoor
11. Cultivation and Utilization of Medicinal Plants by Atal & Kapoor
12. Text book of Pharmacognosy by Steiniger and Hansel
13. Text book of Pharmacognosy by Ramsted
14. Powdered Vegetable Drugs by B.P.Jeckson & D.W.Snewden
15. Practical Pharmacognosy by Iyenger
16. Practical Pharmacognosy by C.K.Kokate
17. I.P., B.P., U.S.P.,
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Second B. Pharmacy
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207 Pharmaceutical Jurisprudence & Ethics [Theory]
1. Introduction [ 2 ]
i. Pharmaceutical Legislation - A brief review.
ii. Drugs & Pharmaceutical Industry -A brief review.
iii. Pharmaceutical Education - A brief review.
2. An elaborate [practical oriented] study of the following ; [ 23 ]
i. Pharmaceutical Ethics
ii. Pharmacy Act 1948.
iii. Drug and Cosmetics Act 1940 and Rules 1945
iv. Medicinal & Toilet preparations [Excise Duties] Act 1955
v. Narcotic Drugs & Psychotropic Substance Act 1985 & Rules
vi. Drug price control order 1995. [DPCO].
3. A brief study of the following with special reference to the main [ 22 ] provisions.
i. Poisons Act 1991.
ii. Drugs and Magic Remedies [Objectionable Advertisements] Act 1954.
iii. Medical termination of Pregnancy Act 1970 & Rules 1975.
iv. Prevention of cruelty to Animals Act 1960.
v. States shops & Establishment Act & Rules.
vi. Insecticides Act 1968.
vii. AICTE Act 1987.
viii. Factories Act 1948.
ix. Minimum Wages Act 1948 & Rules 1950.
x. Patents Act 1970 & Rules 1972.
xi. Consumer Protection Act
4. A brief study of the various prescription/Non-prescription products, [ 1 ]
Medical/surgical accessories, Diagnostic aids, Appliances available in the market.
Note : The teaching of all the above Acts should cover the latest amendments.
Books Recommended:
1. Original laws published by the Government of India.
2. Textbook of Forensic Pharmacy by B.M. Mithal
3 Textbook of Forensic Pharmacy by N.K. Jain
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Second B. Pharm
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